Carotid Atherosclerosis in Predicting Coronary Artery Disease

Objective: This meta-analysis aims to compare the relationship between phenotypic manifestation of coronary and carotid atherosclerosis using available imaging techniques. Approach Results: We searched all electronic databases until October 2020 for studies which reported atherosclerosis. The primary end point was correlation intima-media thickness (CIMT) plaque features (calcification lipid-rich necrotic core) with artery disease (CAD). Secondary points included pathology that predicts CAD. Eighty-nine papers 22 683 patients comparing were in analysis. CIMT increased linearly severity CAD irrespective its significance ( P <0.001), mono versus 2 vessel =0.003), multivessel <0.001). Carotid presence calcification less, core highly prevalent nonsignificant significant <0.001, =0.03, respectively). Moderate found r =0.60, <0.001) number diseased vessels =0.49, There a moderate stenosis =0.53, =0.61, ≥1.0 mm summary sensitivity 77% specificity 72% respective values 80% 67% best predictors CAD, technique used diagnosis. Conclusions: These results support concept affects both systems, although not always identical manner. findings highlight beneficial examination arteries whenever is suspected.